We'll follow US-421 through southeastern KY into VA to Pennington Gap then to Middelsboro, KY and back up US 25 (https://maps.harley-davidson.com/share/rides/cN7g9bJ5jU).

It's 365 miles and we'll stop for a late lunch around 3 PM at The Dutch Treat restaurant (https://www.thedutchtreat.biz/) in Rose Hill, VA.